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Genome Database of Latvian Population [LGDB] Download as PDF

GENERAL INFORMATION

Name Genome Database of Latvian Population
Acronym LGDB
Last update 09/11/2013

Affiliation

    Principal investigators

    Valdis Pirags (Prof. (principal investigator))
    University of Latvia
    Elmars Grens (Prof.(Principal investigator))
    Latvian Biomedical Reasearch and study centre
    Janis Klovins (Dr. (Principal investigator))
    Latvian Biomedical Reasearch and study centre

    Contact

    Nikitina - Zake Liene (Senior Researcher)
    Latvian Biomedical Research and Study Center
    Phone: +371 26111290
    Email:

    Website

    • http://biomed.lu.lv/geneExternal

    Funding agency

    Percentage Category
    Ministry of Health, Latvia 100% Government

    OBJECTIVES

    Main goal of the project is to create a national system of genomic and health information storage and data processing. Genome Database of Latvian Population will serve as a long term public resource for genetic research in Latvia available for researchers. The aim of the study is to promote the creation of a network of genetic epidemiology and pharmacogenetic projects in Latvia and facilitate international collaboration. Genome Database of Latvian Population is involved in development of proposals for governmental institutions to improve the existing legislation concerning the protection of human genome data and molecular testing.

    Research Focus

    • Yes Broad approach with no specific target of interest (study built as an infrastructure for a broad range of unspecified scientific activities/questions).
    • No Target specific questions of interest (predefined scientific targets like, cardiovascular diseases, social environment, specific health trajectories etc.)

    METHODS

    Legend Yes No Unknown

    General design

    Study design Cross-sectional prevalence
    Type of participants Individuals
    Supplementary informations Follow up study planned. At present cross-sectional design is applied, however participants are asked in consent form for permission to access their medical data from registries and hospital records in future.
    Target or final number of participants 60000
      At baseline, population based involvement is applied. However, in order to increase representation of broad range of diseases in biobank other studies separate case-control as well as cohort studies are included through collaboration if they fulfill the minimal requirements for data and biological samples.
    Target or final number of DNA 60000

    Participant selection / Characteristics of the population

    Selection criteria

    Yes Age Minimun: 18 years    Maximun: 95 years
    Yes Country of residence Latvia

    Data Sources

      Cross-sectional Longitudinal follow-up
    Yes Questionnaires to participants/respondents Yes No
    Yes Direct physical measures Yes No
    Yes Biological samples Yes No

    Sample management

    Biological samples

    Yes Blood No Buccal cells
    No Cord blood Yes Tissues (Tumor specific tissues in some cases.)
    Unknown Saliva Unknown Urine

    Genome-Wide Association (GWA) analyses

    • Yes Already or currently generating GWA data. Approximate number of participants : 95

    GOVERNANCE

    Legend Yes No

    Allow access to data or samples to external researchers

    Academia Industry
    Yes Data (questionnaire-derived, measured…) Yes
    Yes Biological samples Yes

    STATUS

    Current status

    Phase Start End
    Preparation phase/Pilot 2003 2005
    Baseline recruitment / initial data collection 2006 2012
    Follow-up of participants -- --
    Current number of participants recruited 20126 in date of 11/14/2012
    Current number of collected DNA samples 20126 in date of 11/14/2012

    This Catalogue was archived on: 2013-12-09. Information included in this Catalogue is for informational purposes only.

    General Information

    Name Health and heredity questionnaire
    Last update 01/21/2010
    Version or reference year 2006
    Phase Baseline
    Year interval 2006 to 2009

    Questionnaire owner

    • Biomedical Research and Study Center

    Contact

    Janis Klovins (Dr. (Principal investigator))
    Latvian Biomedical Research and Study Center
    Riga LV 1067
    Phone: +371 67473083
    Email:

    Methods

    Legend Yes No

    Respondent

    • Yes Participant
    • No Proxy

    Administration environment

    • No Over the phone
    • Yes Hospital, clinic, university or recruitment center
    • No Respondent / Proxy residence

    Administration mode

    • No Auto administered
    • No Auto administrated with face to face validation by trained personnel
    • Yes Administrated by trained personel / Physician

    Administration format

    • Yes Paper questionnaire
    • Yes Computerized

    Administration language

    • Latvian

    Documents

    Available Format

    • Adapted questionnaireWeb page
    • questionaire_for datashaper-01Excel

    NOTICE: HTML document format may differ slightly from the actual questionnaire. Please refer to the original PDF document for exact reproduction.

    General Information

    Name Health and heredity questionnaire
    Number of Question Blocks 25

    Questionnaire and Question Block List

    Click on the View block to see the block of questions related to a domain or a group of domains.
    Block 1 View block
    • Sociodemographic Characteristics / Gender
    Block 2 View block
    • Sociodemographic Characteristics / Age/Birth Date / Subject age / birth date
    Block 3 View block
    • Sociodemographic Characteristics / Birth location / Subject's birth location
    Block 4 View block
    • Sociodemographic Characteristics / Birth location / Subject's family's birth location
    Block 5 View block
    • Sociodemographic Characteristics / Citizenship
    Block 6 View block
    • Sociodemographic Characteristics / Household Status / Subjet Household Status
    Block 7 View block
    • Sociodemographic Characteristics / Household Status / Structure of the Household
    Block 8 View block
    • Sociodemographic Characteristics / Kinship
    Block 9 View block
    • Health Information / Reproductive history / Number of children
    Block 10 View block
    • Socioeconomic Characteristics / Education level / Subject education level
    Block 11 View block
    • Physical Environment / Occupational Exposures / Physical Occupational Exposures / Radiation (ionizing and non ionizing)
    Block 12 View block
    • Physical Environment / Environmental exposures
    • Physical Environment / Occupational Exposures
    Block 13 View block
    • Health Information / Individual Disease history / Injury, poisoning and certain other consequences of external causes
    Block 14 View block
    • Health Information / Medication Intake (ATC/DDD)
    Block 15 View block
    • Life Habits/Behaviours / Tobacco use
    Block 16 View block
    • Physical Environment / Environmental exposures / Chemical environmental exposures / Passive Smoke Exposure
    Block 17 View block
    • Life Habits/Behaviours / Alcohol use
    Block 19 View block
    • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
    Block 20 View block
    • Health Information / Individual Disease history / Neoplasms
    • Health Information / Familial Disease History (ICD10*) / Neoplasms
    Block 21 View block
    • Health Information / Familial Disease History (ICD10*) / Diseases of the circulatory system
    • Health Information / Individual Disease history / Diseases of the circulatory system
    Block 22 View block
    • Health Information / Familial Disease History (ICD10*) / Endocrine, nutritional and metabolic diseases
    • Health Information / Individual Disease history / Endocrine, nutritional and metabolic diseases
    Block 23 View block
    • Health Information / Individual Disease history / Diseases of the circulatory system
    • Health Information / Familial Disease History (ICD10*) / Diseases of the circulatory system
    Block 24 View block
    • Health Information / Familial Disease History (ICD10*) / Endocrine, nutritional and metabolic diseases
    • Health Information / Individual Disease history / Endocrine, nutritional and metabolic diseases
    Block 25 View block
    • Health Information / Familial Disease History (ICD10*)
    • Health Information / Individual Disease history
    Block 26 View block
    • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions

    This Catalogue was archived on: 2013-12-09. Information included in this Catalogue is for informational purposes only.

    GENERAL INFORMATION

    Study name Genome Database of Latvian Population [LGDB]
    Last update 01/26/2010
    Collected at phase Baseline

    Contact

    Janis Klovins (Dr. (Principal investigator))
    Latvian Biomedical Reasearch and study centre
    Riga LV 1067
    Phone: +371 67473083
    Email:

    Physical and cognitive measures collected

    Legend Yes No

    BODY STRUCTURES

    ANTHROPOMETRIC STRUCTURES

    Anthropometric measures

    Yes Weight

    Yes Height

    Yes Standing height

    Yes Body circumferences

    Yes Waist circumference

    BODY FUNCTIONS

    FUNCTIONS OF THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS

    Functions of the cardiovascular system

    Yes Blood pressure (Measured twice)

    Yes Heart rate

    Yes Heart rate at rest

    Administration mode

    Legend Yes No

    Administration environment

    Yes Hospital, clinic, university or recruitment center

    No Participant residence

    No Other

    Staff administering test

    Yes Professionals (nurses, clinicians, etc)

    Yes Interviewers/research assistants

    No Other

    Documentation on procedures

    Administration language Latvian

    GENERAL INFORMATION

    Study name Genome Database of Latvian Population [LGDB]
    Last update 01/31/2012

    Contact

    Zake Liene Nikitna (Senior Researcher)
    Latvian Biomedical Reasearch and study centre
    Riga LV-1067
    Phone: 37126111290
    Email:
    Janis Klovins (Head of the Genome Center)
    Latvian Biomedical Reasearch and study centre
    Riga LV-1067
    Phone: 371 26438469
    Email:

    ACCESS

    Legend Yes No

    Data or samples can be accessed by researchers outside the study/biobank (i.e. a researcher who is not an internal researcher of the study/biobank with research privileges)

    • Yes Access to at least part of the collected data is available for researchers outside the study

    Data/samples can leave the study/biobank facility/country under the policies and regulations of your study

    Data

    • Yes Can leave study/biobank facility
    • Yes Can leave the country

    Samples

    • Yes Can leave study/biobank facility
    • Yes Can leave the country

    Additional information

    Agreement of Participant to send the samples abroad is needed. Restrictions are mentioned in the Consent form. Data and Samples are coded.

    Unknown Participants can not be contacted for additional information or sampling

    Restriction to the category/type of investigator requesting access to your study

    Data

    • Yes Access to data may be granted only to investigators inside the country
    • Yes Access to data may be granted only to investigators contributing to the study (with research privileges)
    • No Access to data may be granted only to Investigators affiliated with academic, non-profit or public institutions
    • Yes Other restrictions to investigators access (Investigators outside the country and from the public sector.)

    Samples

    • Yes Access to samples may be granted only to investigators inside the country
    • Yes Access to samples may be granted only to investigators contributing to the study (with research privileges)
    • No Access to samples may be granted only to Investigators affiliated with academic, non-profit or public institutions
    • Yes Other restrictions to investigators access (Investigators outside the country and from the public sector.)

    Limitations regarding the scientific scope of the projects that can use the study's data/samples

    • Yes Scope of the projects using the data of the study is limited (Yes, participant restricts the use of data. Conditions of restriction are mentioned in the consent form.)
    • Yes Scope of the projects using the samples of the study is limited (Yes, participant restricts the use of samples. Conditions of restriction are mentioned in the consent form..)

    ADDITIONAL INFORMATIONS

    Legend Yes No

    Approval process leading to access

    To grant access, the study requires approval/authorization/documents by the following entities of the applicant's institution

    • No Ethics committee of applicant's institution (or another organization having jurisdiction or required by local governance rules)
    • No Scientific committee of applicant's institution (or another organization having jurisdiction or required by local governance rules)
    • Yes Others (Central Committee of Medical Ethics, Republic of Latvia)

    To grant access, the study requires approval/authorization/documents by the following entities of the study

    • No Ethics committee having jurisdiction over the study/biobank
    • Yes Scientific committee having jurisdiction over the study/biobank
    • Yes Another local committee/organization relevant to the study (Approval by an access committee)

    Information regarding fees to access data/samples

    Data

    There is no fee to access data

    Samples

    • No There are fixed fees to access samples
    • Yes There are scalable fees to access samples varying according to the investigator (e.g. national investigators, students, public/private institutions, etc.)

    To protect confidentiality, access will be provided in the following format

    • No Samples are anonymized (irreversible�destruction of the identity of the participant)
    • No Data is anonymised (irreversible�destruction of the identity of the participant)
    • Yes Samples are coded (identification by a code(s), with possible�reversible�process to identify the participant)
    • Yes Data are coded (identification by a code(s), with possible�reversible�process to identify the participant)

    Investigators will be have to

    • No Submit their publications (articles, presentation, etc) to the study for review prior to public disclosure
    • No Periodically report to the study on the uses of data/samples and/or publications made possible thanks to the use of this research material
    • No Recognize the study as a co-author on their publication
    • No Acknowledge the study in their publication (either in the text or in the footnotes)
    • Yes Others (Agreement of Participant to send the samples abroad is needed. Restrictions are mentioned in the Consent form. Data and Samples are coded.)

    Study in-house analysis services

      Offered Mandatory
    In-house laboratory analysis for applicants Yes No
    In-house statistical analysis for applicants No No

    © 2005 Public Population Project in Genomics.
    All rights reserved.
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