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Ontario Health Study [OHS] Download as PDF

GENERAL INFORMATION

Name Ontario Health Study
Acronym OHS
Last update 01/18/2010

Affiliation

Principal investigators

John McLaughlin (PI/Dr.)
Cancer Care Ontario
Sandra Sinclair (Director Operations, OHS)
Cancer Care Ontario

Contacts

Sandra Sinclair (Director Operations, OHS)
Cancer Care Ontario
Toronto M5G 2L7
Phone: 416 971 9800 x 3154
Email: sandra.sinclair@cancercare.on.caMail
John McLaughlin (PI/Dr.)
Cancer Care Ontario
Toronto M5G 2L7
Phone: 416 971 9800 x1234
Email: john.mclaughlin@cancercare.on.caMail

Website

Funding agencies

  • Ontario Institute for Cancer Research
  • Canadian Partnership Against Cancer
  • Cancer Care Ontario

BACKGROUND

The OHS is a joint project of Cancer Care Ontario, the Ontario Institute for Cancer Research, and the Canadian Partnership Against Cancer that, between 2009 and 2012, will recruit 150,000 Ontarians aged 35-69, who will be followed for 20 or more years. Data collected in the OHS include information about individuals, their environment and their communities, and will encompass the cultural, ethnic and geographic diversity of the province. The purpose of the study is to better understand the risk factors for and causes of cancer and other chronic diseases. The OHS is one of 5 similar cohort studies being conducted across Canada as the 300,000 subject, The Canadian Partnership for Tomorrow Project which is exploring the role of genetics, lifestyle, behaviour and the environment play in the development of cancer.

OBJECTIVES

To better understand the causes of and risk factors for cancer and other chronic disease.

Topics of interest

  • No Broad approach with no specific topic of interest
  • Yes Target specific topics of interest (health outcomes, health determinants, etc.) (Chronic diseases, causes, risk factors, adult)

METHODS

Legend Yes No Unknown

General design

Study design Cohort
Type of participants Individuals
Target or final number of participants 150000
Target or final number of DNA 150000

Participant selection / Characteristics of the population

Selection criteria

Yes Age Minimun: 35 years    Maximun: 69 years
Yes Country of residence Canada (Province of Ontario)
Yes Other criteria Only exclusion noted to date is incarceration.

Supplementary informations

Considering the ethnic diversity of the province, including aboriginal communities, south and south east Asian peoples.

Recruitment procedures

Based on the 16 geographically dispersed communities across the province of Ontario which we have selected for the assessment centre sites, letters of invitation are sent to residents of the surrounding area within a 50 K radius. Addresses are accessed from an electronic, publically available data base. Letters invite potential participants to view the web site or contact the call centre for an appointment or more information. Letters are followed by a 3 weeks reminder post card .Those who book an appointment for an assessment receive an information package by mail and a 48 hr reminder call.

Data Sources

  Cross-sectional Repeated/continuous
Yes Questionnaires to participants/respondents No Yes
Yes Direct physical measures No Yes
Yes Biological samples No Yes
Yes Medical paper
Yes Electronic databases
No Genealogical records  

Collection procedures

Initial data collection takes place at a community based assessment centre. It includes self reported questionnaire on demographics, life style, some personal and family medical history; nurse interview on contra indications for physical measures or phlebotomy, BP, review of current medications and detailed medical history; physical measures including spirometry, bone fragility , BMI, etc; biospecimen collection blood ( or saliva) and urine. Post assessment data is collected by mailed questionnaire including physical activity, dietary information, occupational and residential history.

Follow up procedures

Follow up data collection has not yet been finalized. At this point we anticipate a short annual follow up by telephone, mail or email. Five year follow up of a sample of the participants which involves more comprehensive data collection and repeat specimen collection is planned pending funding .

Baseline principal variables of interest

Health information

  • Yes Diseases history - ICD-10
  • Yes Medication intake
  • Yes Familial disease history
  • Yes Early life
  • Yes Women's health
  • Yes Quality of life

Physical / Biochemical measures

Yes Body structure measures No Biochemical measures
Yes Body function measures  

Sociodemographic Characteristics

Yes Birth location Yes Parents birth location
Yes Ethnicity/Race Yes Gender
Yes Marital status Yes Date of birth

Socioeconomic Characteristics

Yes Education level Yes Income
Yes Working status  

Life habits / Behaviours

Yes Physical activity Yes Smoking / Tobacco Use
Yes Nutrition Yes Alcohol intake

Physical environment

Yes Passive smoking Yes Mobile phone use

Other variables of interest

Vitamins & Minerals, Herbal Supplements, Housing characteristics, Religion & Spirituality, Oral Health, Men’s Health, Emotional Health, Sleep, Sun Exposure, Mental Exercise, Chemical exposures, Community-level measures, Occupational History, Residential History

Sample management

Biological samples

Yes Blood No Buccal cells
No Cord blood No Tissues
Yes Saliva Yes Urine

Biological samples format

  Fresh Frozen Dried (paper) Other Specification
Blood No Yes Yes No
Other No Yes No No Yes (White blood cells)

Genome-Wide Association (GWA) analyses

  • Yes Plan to proceed to GWA analyses later

GOVERNANCE

Legend Yes No

Allow access to data or samples to external researchers

Yes Data (questionnaire-derived, measured…)
Yes Biological samples

STATUS

Current status

Phase Start End
Preparation phase/Pilot 2009 2009
Recruitment / initial data collection 2009 2012
Follow-up of participants -- --
Study ended   2012
Current number of participants recruited 4200 in date of 01/01/2010
Current number of collected DNA samples 4200 in date of 01/01/2010

AVAILABLE DOCUMENTS

  Document type Availability
1 General study protocol john.McLaughlin @cancercare.on.caMail
2 Specific protocols/procedures (data collection, samples management, etc.) sandra.sinclair @cancercare.on.caMail
3 Questionnaires sandra.sinclair @cancercare.on.caMail
4 Consent forms
5 Pamphlet / project description
6 Governance / ethics documentation Kelly.mcdonald@cancercare.on.caMail

General Information

Name Ontario Health Study - Baseline Questionnaire
Last update 09/25/2009
Version or reference year Version 1 (02/09)
Phase Pilot Study
Year interval 2009 to --

Questionnaire owner

  • Ontario Health Study

Contact

Sandra Sinclair (Director Operations, OHS)
Ontario Health Study
Toronto M5G 2L7
Phone: 416 971 9800 x 3154
Email: sandra.sinclair@cancercare.on.caMail

Utilization conditions

None

Methods

Legend Yes No

Respondent

  • Yes Participant
  • No Proxy

Administration environment

  • No Over the phone
  • Yes Hospital, clinic, university or recruitment center
  • No Respondent / Proxy residence

Administration mode

  • Yes Auto administered
  • No Auto administrated with face to face validation by trained personnel
  • No Administrated by trained personel / Physician

Administration format

  • Yes Paper questionnaire
  • Yes Computerized

Administration language

  • Chinese
  • English
  • French

Documents

Available Format

  • Adapted questionnaireWeb page
  • OHS Qx_v2_April0109Word

NOTICE: HTML document format may differ slightly from the actual questionnaire. Please refer to the original PDF document for exact reproduction.

Comment

The questionnaire is also available in Punjabi.

General Information

Name Ontario Health Study - Baseline Questionnaire
Number of Question Blocks 61

Questionnaire and Question Block List

Click on the View block to see the block of questions related to a domain or a group of domains.
Block 1 View block
  • Sociodemographic Characteristics / Age/Birth Date / Subject age / birth date
Block 2 View block
  • Sociodemographic Characteristics / Gender
Block 3 View block
  • Socioeconomic Characteristics / Education level / Subject education level
Block 4 View block
  • Socioeconomic Characteristics / Working status / Subject Working status/history
Block 5 View block
  • Sociodemographic Characteristics / Residence / Current Residence
  • Sociodemographic Characteristics / Residence / Residential History
Block 7 View block
  • Life Habits/Behaviours / Nutrition / Food intake and Frequency / Water Intake
  • Physical Environment / Environmental exposures / Biological environmental exposures / Others
  • Physical Environment / Environmental exposures / Chemical environmental exposures / Others
  • Socioeconomic Characteristics / Income
Block 9 View block
  • Sociodemographic Characteristics / Household Status / Subjet Household Status
Block 10 View block
  • Sociodemographic Characteristics / Kinship
Block 12 View block
  • Sociodemographic Characteristics / Language
Block 13 View block
  • Sociodemographic Characteristics / Ethnicity/Race
Block 14 View block
  • Sociodemographic Characteristics / Household Status / Structure of the Household
  • Socioeconomic Characteristics / Income
Block 15 View block
  • Sociodemographic Characteristics / Religion
Block 16 View block
  • Body structures / Anthropometric structures / Anthropometric measures / Weight
  • Health Information / Participants Early Life Conditions / Participant's Birth weight
Block 17 View block
  • Life Habits/Behaviours / Early life/childhood / History of Being Breastfed
Block 18 View block
  • Health Information / Medical Health Intervention (C239)
Block 19 View block
  • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions
  • Health Information / Medication Intake (ATC/DDD) / Various
Block 20 View block
  • Health Information / Individual Disease history / Injury, poisoning and certain other consequences of external causes
Block 21 View block
  • Health Information / Individual Disease history / Diseases of the musculoskeletal system and connective tissue
  • Health Information / Individual Disease history / Injury, poisoning and certain other consequences of external causes
Block 22 View block
  • Health Information / Individual Disease history / Injury, poisoning and certain other consequences of external causes
Block 23 View block
  • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions / Other Healthcare Interventions, Personal Care
Block 24 View block
  • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions
Block 25 View block
  • Health Information / Women's health / Menstruation
Block 26 View block
  • Health Information / Medication Intake (ATC/DDD) / Genito urinary system and sex hormones (G)
Block 27 View block
  • Health Information / Reproductive history / Number of children
  • Health Information / Reproductive history / Parity/Gravidity
Block 29 View block
  • Health Information / Women's health / Breast feeding
Block 30 View block
  • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions / Therapeutic Interventions on the Genitourinary System
  • Health Information / Medication Intake (ATC/DDD) / Genito urinary system and sex hormones (G)
Block 31 View block
  • Health Information / Women's health / Menopause
Block 32 View block
  • Health Information / Medication Intake (ATC/DDD) / Genito urinary system and sex hormones (G)
Block 33 View block
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions / Therapeutic Interventions on the Genitourinary System
Block 36 View block
  • Health Information / Medical Health Intervention (C239) / Clinical Laboratory Interventions
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Genitourinary System
Block 37 View block
  • Health Information / Medical Health Intervention (C239) / Diagnostic Imaging Interventions / Diagnostic Imaging Interventions on the Skin, Subcutaneous Tissue, and Breast
Block 38 View block
  • Health Information / Medical Health Intervention (C239) / Clinical Laboratory Interventions
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Digestive and Hepatobiliary Tract
Block 39 View block
  • Health Information / Medical Health Intervention (C239) / Diagnostic Imaging Interventions / Diagnostic Imaging Interventions on the Digestive and Hepatobiliary Tract
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Digestive and Hepatobiliary Tract
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions / Therapeutic Interventions on the Digestive and Hepatobiliary Tract
Block 40 View block
  • Health Information / Individual Disease history / Diseases of the genitourinary system
  • Health Information / Men's health
  • Health Information / Reproductive history / Number of children
Block 41 View block
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Genitourinary System
Block 42 View block
  • Health Information / Medical Health Intervention (C239) / Clinical Laboratory Interventions
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Genitourinary System
Block 43 View block
  • Health Information / Medical Health Intervention (C239) / Clinical Laboratory Interventions
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Digestive and Hepatobiliary Tract
Block 44 View block
  • Health Information / Individual Disease history / Diseases of the digestive system
  • Health Information / Medical Health Intervention (C239) / Diagnostic Imaging Interventions / Diagnostic Imaging Interventions on the Digestive and Hepatobiliary Tract
  • Health Information / Medical Health Intervention (C239) / Diagnostic Interventions / Diagnostic Interventions on the Digestive and Hepatobiliary Tract
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions / Therapeutic Interventions on the Digestive and Hepatobiliary Tract
Block 45 View block
  • Health Information / Perception of health/quality of life
Block 46 View block
  • Health Information / Medical Health Intervention (C239) / Cognitive, Psychosocial and Sensory Therapeutic Interventions / Therapeutic Interventions on the Psyche (mental health)
  • Health Information / Medical Health Intervention (C239) / Other Healthcare Interventions
  • Health Information / Perception of health/quality of life
  • Social Environment / Familial and social environment
  • Social Environment / Working Social Environment
Block 47 View block
  • Social Environment
Block 48 View block
  • Social Environment / Familial and social environment
Block 49 View block
  • Life Habits/Behaviours / Sleep Behaviours
Block 50 View block
  • Life Habits/Behaviours / Tobacco use
Block 52 View block
  • Physical Environment / Environmental exposures / Chemical environmental exposures / Passive Smoke Exposure
  • Physical Environment / Occupational Exposures / Chemical Occupational Exposures / Passive Smoke Exposure
Block 55 View block
  • Life Habits/Behaviours / Nutrition / Food intake and Frequency / Beverages (other than water or alcohol)
  • Life Habits/Behaviours / Nutrition / Food intake and Frequency / Vegetables and Fruits
Block 56 View block
  • Life Habits/Behaviours / Alcohol use
Block 57 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
  • Socioeconomic Characteristics / Working status / Subject Working status/history
Block 61 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
  • Life Habits/Behaviours / Travel History and Habits
Block 64 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
Block 67 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
Block 70 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
Block 71 View block
  • Body structures / Hair
Block 72 View block
  • Body structures / Skin
  • Physical Environment / Environmental exposures / Physical environmental exposures / Radiation (ionizing and non ionizing)
Block 77 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
Block 78 View block
  • Physical Environment / Environmental exposures / Chemical environmental exposures / Others
Block 83 View block
  • Physical Environment / Environmental exposures / Physical environmental exposures / Radiation (ionizing and non ionizing)
  • Physical Environment / Occupational Exposures / Physical Occupational Exposures / Radiation (ionizing and non ionizing)
Block 85 View block
  • Life Habits/Behaviours / Physical activity / Activities/Exercise and Frequency
  • Life Habits/Behaviours / Travel History and Habits
Block 86 View block
  • Social Environment / Familial and social environment
Block 87 View block
  • Health Information / Perception of health/quality of life
  • Health Information / Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified / General symptoms and signs
  • Health Information / Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified / Symptoms and signs involving cognition, perception, emotional state and behaviour
Block 88 View block
  • Socioeconomic Characteristics / Income

General Information

Name Ontario Health Study – Nurse Interview
Last update 11/05/2009
Version or reference year Version 1 (02/09)
Phase Pilot Study
Year interval 2009 to --

Questionnaire owner

  • Ontario Health Study

Contact

Sandra Sinclair (Director Operations, OHS)
Ontario Health Study
Toronto M5G 2L7
Phone: 416 971 9800 x 3154
Email: sandra.sinclair@cancercare.on.caMail

Utilization conditions

None

Methods

Legend Yes No

Respondent

  • Yes Participant
  • No Proxy

Administration environment

  • No Over the phone
  • Yes Hospital, clinic, university or recruitment center
  • No Respondent / Proxy residence

Administration mode

  • No Auto administered
  • No Auto administrated with face to face validation by trained personnel
  • Yes Administrated by trained personel / Physician

Administration format

  • Yes Paper questionnaire
  • Yes Computerized

Administration language

  • Chinese
  • English
  • French

Documents

Available Format

NOTICE: HTML document format may differ slightly from the actual questionnaire. Please refer to the original PDF document for exact reproduction.

Comment

The questionnaire is also available in Punjabi.

General Information

Name Ontario Health Study – Nurse Interview
Number of Question Blocks 32

Questionnaire and Question Block List

Click on the View block to see the block of questions related to a domain or a group of domains.
Block 1 View block
  • Socioeconomic Characteristics / Working status / Subject Working status/history
Block 2 View block
  • Sociodemographic Characteristics / Birth location / Subject's birth location
Block 3 View block
  • Sociodemographic Characteristics / Residence / Residential History
Block 5 View block
  • Sociodemographic Characteristics / Birth location / Subject's family's birth location
Block 6 View block
  • Health Information / Individual Disease history / Diseases of the circulatory system
  • Health Information / Individual Disease history / Diseases of the nervous system
  • Health Information / Individual Disease history / Endocrine, nutritional and metabolic diseases
Block 7 View block
  • Health Information / Individual Disease history / Endocrine, nutritional and metabolic diseases
  • Health Information / Individual Disease history / Pregnancy, childbirth and the puerperium
Block 8 View block
  • Health Information / Individual Disease history / Diseases of the musculoskeletal system and connective tissue
Block 9 View block
  • Health Information / Individual Disease history / Diseases of the skin and subcutaneous tissue
Block 11 View block
  • Health Information / Individual Disease history / Certain infectious and parasitic diseases
  • Health Information / Individual Disease history / Diseases of the digestive system
Block 12 View block
  • Health Information / Individual Disease history / Certain infectious and parasitic diseases
  • Health Information / Individual Disease history / Diseases of the respiratory system
Block 13 View block
  • Health Information / Individual Disease history / Diseases of the nervous system
Block 14 View block
  • Health Information / Individual Disease history / Diseases of the eye and adnexa
Block 15 View block
  • Health Information / Individual Disease history / Diseases of the genitourinary system
Block 16 View block
  • Health Information / Individual Disease history / Certain infectious and parasitic diseases
Block 17 View block
  • Health Information / Individual Disease history / Neoplasms
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions
Block 18 View block
  • Health Information / Medical Health Intervention (C239) / Physical/Physiological Therapeutic Interventions / Therapeutic Interventions on the Cardiovascular System
Block 19 View block
  • Health Information / Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified / Symptoms and signs involving the circulatory and respiratory systems
Block 20 View block
  • Health Information / Individual Disease history
Block 21 View block
  • Health Information / Medical Health Intervention (C239)
Block 22 View block
  • Health Information / Medication Intake (ATC/DDD)
Block 23 View block
  • Health Information / Medication Intake (ATC/DDD) / Various
  • Life Habits/Behaviours / Nutrition / Food intake and Frequency / Salt and Food Supplement
Block 25 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the circulatory system
Block 26 View block
  • Sociodemographic Characteristics / Kinship
Block 27 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the circulatory system
Block 28 View block
  • Health Information / Familial Disease History (ICD10*) / Endocrine, nutritional and metabolic diseases
Block 29 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the circulatory system
Block 31 View block
  • Health Information / Familial Disease History (ICD10*) / Mental and behavioural disorders
Block 32 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the respiratory system
Block 35 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the musculoskeletal system and connective tissue
Block 37 View block
  • Health Information / Familial Disease History (ICD10*) / Diseases of the nervous system
Block 38 View block
  • Health Information / Familial Disease History (ICD10*) / Mental and behavioural disorders
Block 39 View block
  • Health Information / Familial Disease History (ICD10*) / Neoplasms

General information

Name Physical and cognitive measures
Last update 09/16/2009
Collected at phase Baseline Data Collection
Year interval 2009 to 2012

Contacts

Kelly McDonald
Cancer Care Ontario
Toronto M5G 2L7
Phone: 416-971-9800 x3268
Email: kelly.mcdonald@cancercare.on.caMail

Physical and cognitive measures collected

Legend Yes No

BODY STRUCTURES

ANTHROPOMETRIC STRUCTURES

Anthropometric measures

Yes Weight

Yes Height

Yes Standing height

Yes Sitting height

Yes Body circumferences

Yes Waist circumference

Yes Hip circumference

Yes Other (Arm-span measurement)

Body composition

Yes Bioimpedance (Segmental bioimpedance)

Yes Bone density (Calcaneal ultrasound)

BODY FUNCTIONS

FUNCTIONS OF THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS

Functions of the cardiovascular system

Yes Blood pressure

Yes Heart rate

Yes Heart rate at rest

Yes Other measures of the cardiovascular functions (Ankle-Brachial Index)

Functions of the respiratory system

Yes Respiratory functions (Spirometry)

NEUROMUSCULOSKELETAL AND MOVEMENT-RELATED FUNCTIONS

Yes Grip strength

HANDEDNESS / LATERALITY

Yes Handedness functions

Administration mode

Legend Yes No

Administration environment

Yes Hospital, clinic, university or recruitment center

No Participant residence

No Other

Staff administering test

Yes Professionals (nurses, clinicians, etc)

Yes Interviewers/research assistants

No Other

Documentation on procedures

Administration language English

Standard operating procedures (SOPs) or reference information

General Information

Name DNA Processing
Study name Ontario Health Study [OHS]
Last update 09/18/2009

Contact

Ontario Health study c/o the Ontario Health Study Operations Team, Cancer Care Ontario
 c/o the Ontario Health Study Operations Team, Cancer Care Ontario
Toronto
Phone: 416-971-9800 x 3470
Utilization conditions Acknowledgement obtained by seeking collaborative support from the OHS Team.

Samples

Legend Yes No
Sample name Blood Buccal cells Other - Urine
  Main laboratory multiple, coordinated by study centre
  Sample labels/traceability (% of samples)
  • No RFID radio frequency identification
  • Yes Barcode (2D)
  • No Printed labels
  • No Handwritten numbers
  • No Others
  • No RFID radio frequency identification
  • Yes Barcode (2D)
  • No Printed labels
  • No Handwritten numbers
  • No Others
  • No RFID radio frequency identification
  • Yes Barcode (2D)
  • No Printed labels
  • No Handwritten numbers
  • No Others
Pre-extraction sample storage format Substrate storage condition
  • No Fresh
  • No Refrigerated
  • No Frozen
  • No Dried (paper)
  • Yes Liquid Nitrogen (gas)
  • No Other
  • No Fresh
  • No Refrigerated
  • Yes Frozen (-4°C)
  • No Dried (paper)
  • No Liquid Nitrogen
  • No Other
  • No Fresh
  • No Refrigerated
  • No Frozen
  • No Dried (paper)
  • Yes Liquid Nitrogen (gas)
  • No Other
Substrate storage period
  • No Short term
  • Yes Long term
  • No Short term
  • Yes Long term
  • No Short term
  • Yes Long term
Laboratory in charge Coordinated through study centre
Protocols using the standard Oragene protocols
DNA extraction DNA extraction method
  • No Salting out
  • No Phenol-chloroform
  • No Columnary-extraction
  • No Magnetic beads
  • No Oragene (saliva)
  • No Others
  • No Salting out
  • No Phenol-chloroform
  • No Columnary-extraction
  • No Magnetic beads
  • No Oragene (saliva)
  • No Others
  • No Salting out
  • No Phenol-chloroform
  • No Columnary-extraction
  • No Magnetic beads
  • No Oragene (saliva)
  • No Others
Automation of handling
  • No Manual
  • No Automated
  • No Manual
  • No Automated
  • No Manual
  • No Automated
DNA handling and storage DNA diluent
  • No TE
  • No H2O
  • No Others
  • No TE
  • No H2O
  • No Others
  • No TE
  • No H2O
  • No Others
DNA concentration (ng/µl)
Storage conditions
  • No 4°C
  • No -20°C
  • No -40°C
  • No -80°C
  • No Dried
  • No Others
  • No 4°C
  • No -20°C
  • No -40°C
  • No -80°C
  • No Dried
  • No Others
  • No 4°C
  • No -20°C
  • No -40°C
  • No -80°C
  • No Dried
  • No Others
DNA quantification Methods
  • No A260/A280
  • No Picogreen
  • No Nanodrop
  • No Others
  • No A260/A280
  • No Picogreen
  • No Nanodrop
  • No Others
  • No A260/A280
  • No Picogreen
  • No Nanodrop
  • No Others
Technical quality
  • No Automated
  • No Manual
  • No Reproducibility
  • No Automated
  • No Manual
  • No Reproducibility
  • No Automated
  • No Manual
  • No Reproducibility
DNA quality control Percentage of samples that are tested
DNA quality method
  • No Agarose gel
  • No PCR
  • No A260/A280 ratio
  • No Others
  • No Agarose gel
  • No PCR
  • No A260/A280 ratio
  • No Others
  • No Agarose gel
  • No PCR
  • No A260/A280 ratio
  • No Others

General Information

Name Information Technologies
Study name Ontario Health Study [OHS]
Last update 09/22/2009

Contact

Bob Zurowski
Ontario Health Study, c/o Cancer Care Ontario
Phone: 416-971-9800 ext. 3869
Email: bob.zurowski@cancercare.on.caMail

Software

Legend Yes No

Software overview

Biobanking areas covered OBiBa Onyx OBiBa Opal
Participant recruitment (ex: CATI, CRM)
Data collection Yes
Sample collection, storage and processing Yes
Data repository Yes
Other Yes
 
Programming language OBiBa Onyx OBiBa Opal
Name and version of programming language Java Java
 
Internal/external development OBiBa Onyx OBiBa Opal
In-house by IT department
By an external company Yes Yes
 
Shareability OBiBa Onyx OBiBa Opal
Freely available Yes Yes
Purchaseable
Needs extensive work
Not for share

Software details

Biobanking areas covered

  • No Participant recruitment (ex: CATI, CRM)
  • Yes Data collection
  • Yes Questionnaires (ex: CAPI)
  • Yes Physical and cognitive measures
  • Yes Sample collection, storage and processing
  • Yes Collection
  • No Sample bio-repository management system (ex: sample storage management software)
  • No LIMS (ex: biochemical analysis, DNA extraction, genotyping)
  • No Data repository
  • No Data warehousing
  • No Study monitoring (ex: quality control)
  • No User data / sample request management
  • Yes Other (Electronic concent)

Name and version of programming language

Java

Internal/external development

  • No In-house by IT department
  • Yes By an external company (OBiBa)

Shareability

  • Yes Freely available
  • No Purchaseable
  • No Needs extensive work
  • No Not for share

Supplementary informations

http://www.obiba.org/onyx/

Biobanking areas covered

  • No Participant recruitment (ex: CATI, CRM)
  • No Data collection
  • No Questionnaires (ex: CAPI)
  • No Physical and cognitive measures
  • No Sample collection, storage and processing
  • No Collection
  • No Sample bio-repository management system (ex: sample storage management software)
  • No LIMS (ex: biochemical analysis, DNA extraction, genotyping)
  • Yes Data repository
  • Yes Data warehousing
  • Yes Study monitoring (ex: quality control)
  • Yes User data / sample request management

Name and version of programming language

Java

Internal/external development

  • No In-house by IT department
  • Yes By an external company (OBiBa)

Shareability

  • Yes Freely available
  • No Purchaseable
  • No Needs extensive work
  • No Not for share

Supplementary informations

http://www.obiba.org/onyx/

Comments

We use an MS Access database for tracking the Laboratory processing of the bio samples within the Lab. It was written by a third party contractor in Visual Basic.

As of September 2009, we are in the process of taking the base components/functionality of GERT and tailoring it for the OHS requirements, for tracking bio samples from Assessment Centre to Laboratory to BioBank. We are still only on requirements gathering phase, it will be developed in Java and made available when complete.

© 2005 Public Population Project in Genomics.
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