Alpha-Tocopherol, Beta-Carotene Cancer Prevention [ATBC]
GENERAL INFORMATION
| Name | Alpha-Tocopherol, Beta-Carotene Cancer Prevention |
|---|---|
| Acronym | ATBC |
| Last update | 03/19/2009 |
Affiliation
- Biobanking and Biomolecular Resources Research Infrastructure [BBMRI]
- National Biobanks of Finland / KTL (The) [KTLBiobanks]
Principal investigator
No information available
Contact
|
Demetrius Albanes
|
National Cancer Institute
Phone: 011-358-0-947-441 Email: daa@nih.gov 
|
Website
OBJECTIVES
To investigate whether daily supplementation with alpha-tocopherol, beta-carotene, or both would reduce the incidence of lung or other cancers among male smokers.
METHODS
Legend
Yes
No
Unknown
|
General design
| Study design | Clinical / intervention trial |
|---|---|
| Type of participants | Individuals, Random assignement of the participants to one of four groups that received for 5-8 years: 1) alpha-tocopherol (50 mg/day), 2) beta-carotene (20 mg/day), 3) both supplements or 4) placebo capsules. |
| Supplementary informations |
Random assignement of the participants to one of four groups that received for 5-8 years:
1) alpha-tocopherol (50 mg/day), 2) beta-carotene (20 mg/day), 3) both supplements or 4) placebo capsules. |
| Target or final number of participants | 29133 |
| Target or final number of DNA | No information available |
Participant selection / Characteristics of the population
Selection criteria
|
Gender
|
Men |
|
Age
|
Minimun: 50 years Maximun: 69 years |
|
Country of residence
|
Finland |
|
Other criteria
|
Men who smoked at least five cigarettes per day and reside in the southwestern Finland. |
STATUS
Current status
| Phase | Start | End |
|---|---|---|
| Preparation phase/Pilot | 1984 | 1985 |
| Recruitment / initial data collection | 1985 | 1988 |
| Follow-up of participants | 1985 | 1993 |
Supplementary informations
Follow-up:
1) three annual visits,
2) at 3 years, food frequency questionnaire,
3) follow-up through Cancer Registry and governmental databases.
Several blood samples from each participant.
| Current number of participants recruited | 29133 |
|---|
| Current number of collected DNA samples | 29133 |
|---|
