Cores
The site provides general information on P3G Cores, and if relevant, link to the projects website.
To become a Core, researchers should submit application to P3G Board
.
If you would like to have more information or add your project to the list, please
contact us
.
International Working Group 1: Genomics and Biochemical Investigations
DNA Quantity and Quality Control (Q2C)
|
Contact person:
|
Martin Yuille
|
|
Main deliverable:
|
International guidelines for DNA measurements.
|
|
Description:
|
International project to harmonize DNA measurements in academic labs and commercial facilities. The aim is to
facilitate the movement of samples between labs by ensuring compatibility of results obtained in quantity and
quality measurements.
|
Harmonization and Quality Control of Lipidomics Analysis
|
Contact person:
|
Gerd Schmitz
|
|
Main deliverable:
|
Guidelines for standardization of approaches in lipidomics science.
|
|
Description:
|
The project aims to foster harmonization of lipid nomenclature and related metabolic pathways as well as
standardization and quality control of Lipidomics analysis in a worldwide effort.
|
International Working Group 2: Knowledge Curation and Information Technology
The Obiba Project
|
Contact person:
|
Vincent Ferretti
|
|
Main deliverable:
|
Website including an integrated suite of open source information management systems.
|
|
Description:
|
The Obiba Project will provide an open source information management system for biobanks that can be used as is, or
be adapted. This information system will support a wide range of biobank activities and will include data exchange
interfaces to facilitate sharing between different installations.
|
International Working Group 3: Ethics, Governance and Public Engagement
P3G Policymaking Core
|
Contact person:
|
Bartha Maria Knoppers
|
|
Main deliverable:
|
Series of papers on: consent/confidentiality and commercialization, data access and use policies, and Governance
models for population biobanks.
|
|
Description:
|
This project aims to take a role in the international discussion and elaboration of policy approaches and
methodologies specific to human genetic epidemiology.
|
ESRC Innogen Centre
|
Contact person:
|
David Wield
|
|
Main deliverable:
|
To produce research advancing the social science knowledge base of the new life science economy.
|
International Working Group 4: Epidemiology and Biostatistics
DataSHaPER (Data Schema and Harmonization Platform for Epidemiological Research)
|
Contact person:
|
Isabel Fortier
|
|
Main deliverable:
|
Interactive tool including a list of variables of particular interest to be used by and shared between emerging
biobanks.
|
|
Description:
|
The DataSHaPER is a comprehensive set of variables that ought ideally to be collected by large epidemiological studies
and biobanks whenever the fundamental aim is to undertake general-purpose biomedical research. The aim of the DataSHaPER
is to provide a template to facilitate harmonization between biobanks and support the design of emerging ones.
|
ESPRESSO Power Calculator
|
Contact person:
|
Paul Burton
|
|
Main deliverable:
|
Publications and a software allowing comprehensive power and sample size calculation.
|
|
Description:
|
ESPRESSO (Estimating
Sample-size and
Power in
R by
Exploring
Simulated
Study
Outcomes) is a new "R"-based program for simulation-based power calculation that can be used to
estimate realistic sample size requirements for case-control and cohort studies in population genomics where
analysis focuses on either direct genetic or environmental effects or interactions.
|
Development of Calibration Studies
|
Contact person:
|
Julian Little
and Muin Khoury
|
|
Main deliverable:
|
Development of methods to calibrate measures of exposure used in different biobanks.
|
Assessment of Disease Outcomes and Intermediate Phenotypes
|
Contact person:
|
Julian Little, Muin Khoury,
Paul Burton
and Isabel Fortier
|
|
Main deliverable:
|
Identification of disease outcomes and intermediate phenotypes that will be comparable between biobanks.
|
