General information

Name European Prospective Investigation into Cancer and Nutrition
Acronym EPIC
Last update 04/09/2009

Principal investigator

Elio Riboli (Dr./PI/Professor)
Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London


Elio Riboli (Dr./PI/Professor)
Department of Epidemiology and Public Health, Imperial College London
London W2 1PG
Phone: +44 (0)20 7594 1913




The EPIC cohort consists of 23 sub-cohorts in 10 European countries (Denmark, France, Greece, Germany, Italy, Netherlands, Norway, Spain, Sweden, United Kingdom), providing a wide range of cancer occurrence rates, lifestyle and dietary habits. In total, 521468 subjects have been enrolled. Country specific dietary questionnaires, as well as standardized lifestyle and personal questionnaires, various anthropometric measures and blood samples (plasma, serum, leukocytes, erythrocytes - all stored in liquid nitrogen) have been collected from most participants. Country specific dietary questionnaires were used in order to ensure high compliance and to obtain better measures of local dietary habits. In addition, detailed 24 hour diet recalls have been collected from a subset (8% random sample; total of 36000 subjects) of all EPIC cohorts for the purpose of calibrating dietary questionnaire data in order to counter estimation errors and differences in questionnaire design and application amongst centers, allowing for estimation of food intakes on a common scale, hence enabling better comparisons of cancer risk. The rationale and detailed methods of the study are described in Nature Reviews on Cancer 4(3):206-215, 2004.


To investigate the role of diet, lifestyle, metabolic factors, environment and genetic predisposition to the etiology of cancer and other chronic diseases.

Member organizations

Design of the member studies Cohort


Associated network

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