Genomic Comparison Chart: Management and Analysis of Genomic Data

The following comparison table describes and compares the content of a series of websites that focus on a number of topics that are central to the management and interpretation of genomic, transcriptomic and proteomic data. These include information and/or tools that are valuable in considering: PCR methodology; SNPs; LD structure; genotyping and haplotyping; gene and genome sequence and structure; and gene expression. The various websites present a mixture of tools and data that are ready to be used. Bioconductor also provides an open source environment, based primarily on the R programming language, in which new tools can be developed and submitted for others.

Genomic websites Broad Institute Software CLC Free Workbench EBI ENCODE project (for a part of the human genome only) GeneSNPs Genetic Associaiton Database HapMap NCBI Seattle SNPs UCSC Bioconductor (open-source platform for software development)
Link http://www.broad.mit.edu/
tools/software.html
External
http://www.clcbio.com/
index.php?id=28
External
http://www.ebi.ac.ukExternal http://genome.ucsc.edu/
ENCODE
External http://www.hapmap.org/
downloads/encode1.html.en
External
http://www.genome.utah.edu/
genesnps
External
http://geneticassociationdb.nih.govExternal http://www.hapmap.org/
index.html.en
External
http://www.ncbi.nlm.nih.govExternal http://pga.gs.washington.eduExternal http://genome.ucsc.edu/
index.html?org=Human&
db=hg18&hgsid=116636913
External
http://www.bioconductor.org/External
Content: Link to other pages or websites Many separate tools: Birdsuite, Arachne, Argo etc. Many separate tools: ArrayExpress, Ensembl etc. Link to NCBI, EBI Link to OpenHelix, NCBI, UCSC, SeattleSNPs Link to NCBI, UCSC, HapMap, HuGENavigator etc. Link to NCBI Many separate tools: Nucleotide, GEO etc. Link to NCBI, HapMap, GVS/GeneSNPs Link to Galaxy Many separate tools
Web-based Browsers : Genome; Proteome; SNPs; Structure; Pathway Genome Genome, Proteome, SNPs, Structure Genome, Proteome, SNPs, Structure, Pathway Genome, Proteome, SNPs, Structure, Pathway Genome, Proteome, SNPs, Structure, Pathway Genome Genome, Proteome, SNPs, Structure SNPs Genome, Proteome Genome
Gene characteristics / structure Data (e.g: variants, exons, introns) GWA karyogram
Sequence data and tools (e.g: alignment blast) Tools Tools Tools Data Tools Tools & Data Data Tools & Data Tools Data Tools
PCR Tools (e.g: in silico PCR, primers, cloning, design)
PCR & Realtime PCR data
Data and tools for Genotype / Haplotype / SNPs Tools Data Data Data Data Data Data (ENCODE) Data Data Data (ENCODE) Tools
Data and tools for gene expression analysis (example of used techniques: microarrays, Western blot, Northern Blot) Tools Data (soon) Data Data Data Data Data Tools
Data and tools for Gene expression regulation analysis (example of used techniques: ChIP, RNAi, ChIP-ChIP) Data Tools Tools & Data Data Data Data Data Tools
LD, Phasing, QTL data
Free access to Wet lab protocols downloadable available available (GEO) available
Gene functions (e.g: litterature review, interaction) GWA karyogram
Download Excel formatExcel
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