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Cores and Foundation Projects

The site provides general information on P³G Cores and foundation projects, and if relevant, link to the projects website. To be included considered as a foundation project, a project has to be a P³G core or be a project of particular interest that is part of the P³G initiative and share similar objectives. To become a Core, researchers must submit application to P3G Boardexternal.

If you would like to have more information or add your project to the list, please .

International Working Group 1: Genomics and Biochemical Investigations

DNA Quantity and Quality Control (Q2C)external
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Main deliverable: International guidelines for DNA measurements.
Description: International project to harmonize DNA measurements in academic labs and commercial facilities. The aim is to facilitate the movement of samples between labs by ensuring compatibility of results obtained in quantity and quality measurements.
Harmonization and Quality Control of Lipidomics Analysis
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Main deliverable: Guidelines for standardization of approaches in lipidomics science.
Description: The project aims to foster harmonization of lipid nomenclature and related metabolic pathways as well as standardization and quality control of Lipidomics analysis in a worldwide effort.

International Working Group 2: Knowledge Curation and Information Technology

The Obiba Projectexternal
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Main deliverable: Website including an integrated suite of open source information management systems.
Description: The Obiba Project will provide an open source information management system for biobanks that can be used as is, or be adapted. This information system will support a wide range of biobank activities and will include data exchange interfaces to facilitate sharing between different installations.

International Working Group 3: Ethics, Governance and Public Engagement

P³G Policymaking Core
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Main deliverable: Series of papers on: consent/confidentiality and commercialization, data access and use policies, and Governance models for population biobanks.
Description: This project aims to take a role in the international discussion and elaboration of policy approaches and methodologies specific to human genetic epidemiology.

International Working Group 4: Epidemiology and Biostatistics

DataSHaPER (Data Schema and Harmonization Platform for Epidemiological Research)
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Main deliverable: Interactive tool including a list of variables of particular interest to be used by and shared between emerging biobanks.
Description: The DataSHaPER is a comprehensive set of variables that ought ideally to be collected by large epidemiological studies and biobanks whenever the fundamental aim is to undertake general-purpose biomedical research. The aim of the DataSHaPER is to provide a template to facilitate harmonization between biobanks and support the design of emerging ones.
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Main deliverable: Website providing a series of tutorials and reviews for analysis of genetic data.
Description: GeneStat provides a knowledge base for statistical genetics through an Internet-based series of tutorials and reviews with links to key sites and computer programs for analysis of genetic data.
ESPRESSO Power Calculator
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Main deliverable: Publications and a software allowing comprehensive power and sample size calculation.
Description: ESPRESSO (Estimating Sample-size and Power in R by Exploring Simulated Study Outcomes) is a new "R"-based program for simulation-based power calculation that can be used to estimate realistic sample size requirements for case-control and cohort studies in population genomics where analysis focuses on either direct genetic or environmental effects or interactions.

P³G Observatory

Study Questionnaire Catalogues
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Main deliverable: Series of web interfaces including the: Study, Questionnaire, Physical and Cognitive Measures, Ethics and Governance and Sample Storage and Processing Catalogues.
Description: The Catalogues provide a quick and easy access to information on practices in population-based biobanks and allow a rapid overview of the similarities and differences, and potential for harmonization between participating biobanks.
Theory and Practices Repository
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Main deliverable: Web interface providing access to reference information and tools in different domains of biobanking.
Description: This tool aims to provide access to technical and scientific information in order to support investigators and biobank administrators in the development and realization of their activities.