Study Catalogue Statistics

• Country of residence
• Selection criteria
• Number of participants targeted
• Study design
• Targeted versus recruited number of participants
• Age of participants at recruitment
• Collected biological samples
• Access to data and samples

Statistics are on data deemed to be accurate at the time of collection from studies

Selection criteria: country of residence (N = 158)

Geographical distribution for single-country studies

		Number of studies	Number of participants TARGETED
Single-country studies	Europe	72	5,632,000
	America	49	4,142,000
	Oceania	7	441,000
	Africa	1	85,000
	Asia	17	1,419,000
Multiple-countries studies	Europe, America, Oceania, Africa, Asia	12	1,068,432

Selection criteria (N = 164)

Selection criteria (independent factors) % of studies Newborn / Gravidity 10 % Gender 14 % Ethnicity 11 % Health status 11 % Twins 4 %

Number of participants targeted (recruited or to be recruited) (N = 141)

Number of participants Number of studies Number of participants TARGETED 10,000 to 49,999 79 1,555,000 50,000 to 99,999 27 1,833,000 100,000 to 499,999 26 3,905,000 500,000 and more 9 5,386,000   Total: 12,679,000 * 17 studies have been excluded from the table because the number of participants ( 107,000 participants targeted)

Number of studies

Study design (N = 158)

Study Design Number of Studies Number of participants TARGETED Registry 0 0 Cohort 129 11,617,000 Case-control 3 126,000 Clinical Trial 7 166,000 Cross-sectional 17 282,000 Others 9 1,162,000

Number of studies

Targeted versus recruited number of participants (N = 154)

Age of participants at recruitment (N = 148)

Collected biological samples (N = 91)

What type of Biological samples are collected?

Collected biological samples Number of studies Blood 85 Cord blood 5 Buccal cells 21 Tissues 17 Saliva 14 Urine 29 Others 16 Categories are not mutually exclusive.

Access to data and samples (N = 80)

Is access to data and samples to external researchers or third parties provided or foreseen?

Access given to: Number of studies Data (Questionnaire-derived, measured...) 73 Biological samples 66 Other 11 Categories are not mutually exclusive.